Dr. A Srinivas Kumar

Educational Qualifications

• D.M. (Cardiology) at Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow in June 1998
• MD (Gen. Med.) at Osmania Medical College, Hyderabad in June 1994
• MBBS at Osmania Medical College, Hyderabad, in December 1989.
• FACC (USA) at ACC, Chicago in 2008

Presently working as

• Senior Consultant Cardiologist, Director Cardiology & Clinical Research, Apollo Hospitals,Jubilee Hills
• Professor of Medicine, ApolloISMR, Hyderabad.
•  Chairman, Facts Professional Services(FPS) & Founder,Director & CEO - FACTS – Fraternity of Advanced Cardiovascular Techniques & solutions- FPS- Largest CV professional group of India.
• Founding Course Director – Advance CardioVascular Solutions – India (ACVS – INDIA)/ TCT INDIA, South Asia Conference.- India’s Premier Interventional Experience,

‍Earlier Experiences

• Professor of General Medicine Prathima Institutte of Medical Sciences,Karimnagar.(2010- 2017)
• Asst. & Associate Professor of General Medicine Prathima Institutte of Medical Sciences, Karimnagar.(2001- 2010)
•  Chairman, CardioVascular Sciences& Chief Cardiologist,Citizens Hospitals, Nallagandla, Hyderabad.(2014-2018)‍
• ‍Chief of Medical Services, Citizens Hospitals(2016-18)
• Senior Consultant Cardiologist, Director, Cardiac Catheterisation laboratory &InvasiveCardiology, Care Hospitals, Banjara Hills, Hyderabad. (2000-2014)
• Directorand Head Clinical Research Department, Caregroup of Hospitals, India.(2008-2014)
• Managing Director,Life Hospitals, Shivam Road, Hyderabad(2012-2014)‍
• ‍Past- President for Andhra Pradesh Cardiology Society of India (APCSI).
• Executive Member, National CSI (2007-9,13-15) (10)National Convenor, CardiacImaging, CSI (2010-12).‍
• Chairman, CSI- National Interventional Council, INDIA( 2018-19).

Awards and credentials

• State IInd Rank in Andhra Pradesh M.B.B.S. Entrance Examination.
• S.R.Rao Research Award for best thesis in M.D.General Medicine “A study of clinical profile of cases of Sickle cell disorder in adults”.
• Founder Editor of National Medical Journal “Post Graduate Medical Clinics of Osmania’’.
• Selected as reviewer for International Journal “Catheterisation & Cardiovascular Diagnosis’’ in 1998.
• President for 2009-10, Cardiological Society of India, AP Chapter.
• Executive Committee member, Cardiological Society of India 2007-09..
• Chairman, CSI- National Interventional Council 2017-19.
• Faculty for training Interventional Cardiologists from USA for Transseptal puncture technique training – St Judes Co. Initiative to train Interventional & EP Cardiologists of USA.
• Faculty for SING LIVE Course in Singapore in 2006-08.
• Faculty for CIT- China Interventional Therapeutics-2009.
• Faculty for CCT-Kobe, Japan-2009.
• Faculty for Angioplasty Summit, Seol, Korea-2010.
• Faculty for TCT,USA -2011,2012.
• Live Case Operator for Procedure Demonstration to TCT,USA 2012,2019.
• Programme Director & Founder of ACVS(Advance CardioVascular Solutions)India//TCT India , South Asia National Conference.
• Scientific advisor and Product concepts & device analyzer for Relysis India, S3V Vascular technologies,Medtronic & Boston Scientific. India..

‍Research

Research experience in multicentre trials

1. ‍PRINCIPAL INVESTIGATOR for Nephric–II Study – ARandomized Comparison of Iapamiro vs. Iopamidal in Diabetic Renal Insufficiency patients-Sponsored by GE Health Care. –Appreciatedas Worlds leading recruiter for enrolling maximumno of patients.‍
2. ‍PRINCIPAL INVESTIGATOR – COREL C Multicentre Stent Study-Paclitaxeleluting, Non-polymeric, Nonporous carbon-carbon coated Cobalt-chromium stent: Clinical and Angiographic Evaluation.Sponsoredby Relysis India Pvt. Ltd. - 2^nd leading recruiter for the study.‍
3. PRINCIPAL INVESTIGATOR- RE-DEEM STUDY – RandomisEd Dabigatran Etexilate dose finding study in patientswith Acute Coronarysyndromes post index Eventwith additional risk factors for cardiovascular complications also receivingasprin and clopidogrel: Multicentre, prospective placebo controlled, groupdose escalation trial-Sponsored byBoehringer Ingelheim.- 2^nd leading recruiter in the world.‍
4.  CO-INVESTIGATOR - a multinational, multicentre, randomized, parallelgroup, Double-blind study to assess the efficacy and safety of 1 mg, 5Mg and 20 mg tid of oral sildenafilin the treatment of Subjects aged 18 years and over with pulmonary arterialHypertension (PAH)- A Multicentre PAH study sponsoredby Pfizer Int. Ltd.-Leading recruiters in the world.
5. ‍PRINCIPAL INVESTIGATOR- SPIRIT WOMEN CLINICAL EVALUATION : A ClinicalEvaluation of the Xience-V Everolimus eluting coronary stent system in the treatment of women withdenovo coronary artery lesion (single armstudy protocol) – Leading recruiter in the world.
6. PRINCIPAL INVESTIGATOR –Xience-V Everolimus eluting coronarystent system (EECSS) India- Post marketing Registry-appreciated for faster enrollment rate permonth.‍
7. PRICIPAL INVESTIGATOR – AMI- Stem cell study – A Randomized, double blind Multicentric, Placebo controlled , Single dose ,Phase-II Study assessing the safety and efficacy of Intravenous ex vivo culturedadult allogenic mesenchymal stem cells in patients with STEMI.- Sponsoredby STEMPEUTICS ResearchLtd.‍
8. CO-INVESTIGATOR. – A Randomized, double blindMulticentric , Placebo controlled ,Single dose , Phase-II Study assessing the safety and efficacy of Intramuscular ex vivo culturedadult allogenic mesenchymal stem cells in patients with CriticalLimb Ischemia.- Sponsoredby STEMPEUTICS ResearchLtd.‍
9. PRINCIPAL INVESTIGATOR).- prospective Evaluation of AdvancedGlycosylation End-products in chronic heart failure patients - Type II DM with stable Heart failure patients( Phase II)‍
10. CO-INVESTIGATOR   -   ART   (Arterial    Revascularisation     Trial) ART is a multi-centre,international, randomized trial evaluating whether the use of both mammary arteries during coronary artery bypassgrafting (CABG) improves survival,and reduces the chance of recurrent chest pain and/or the need for furtherintervention (including surgery)compared to using one mammary artery. ART is supported bygrants from the Medical Research Council and the British Heart Foundation.
11. Evaluation of acute safety and efficacy of the BasalAnnuloplasty Cardia Externally devisein the treatment of Functional Mitral valve Regurgitation ( Phase II)- Experienced in dp/ dt, Experienced in Tissue Doppler Echocardiography.
12. Multicenter Evaluation of Coronary Dual Source CT angiographyin patients with Intermediate Riskof Coronary Artery Stenosis- Leadingrecruiters in World.
13. CEC MEMBER – BIOFLOW- INDIA.

Publications

1. ‍ Immediateand follow up results of Inoue balloon mitral valvotomy in juvenile rheumaticmitral stenosis. N. Sinha A.Kapoor, A.Sreenivas Kumar, M.Shahi, S.Radhakrishnan,S.Shrivastava, P.K.Goel. Journal OfHeart Valve & Disease, 1997, 6:6.
2.  Influenceof Subvalvular pathology on immediate results and follow up events of Inoue balloon mitral valvotomy. A.Sreenivas Kumar, A. Kapoor, N.Sinha,S. Tewari, P.K.Goel, C.V. Umeshan,M.Shahi. Accepted for publication in Int. J. cardiol.
3. Smallaortic annulus: A Functional definition. Probal .K.Ghosh, Sanjeev Kumar, Shantanu Pandey, A.Sreenivas Kumar, N.Sinha, M.Shahi. Annals of Asian cardiovascular and thoracic surgery October 98.
4. Small (<21mm) aortic valve prostheses - A clinical andHemodynamic evaluation. A. SreenivasKumar, PrabhatKumar, M.Shahi, N.Sinha, Sanjeev Kumar, Shantanu Pandey, Probal K.Ghosh. Journalof Heart Valve Disease98..
5. Periodic Intermittent Electromechanical Dissociation:Hemodynamic Correlateof a MalfunctioningMechanical Prostheses Letter to the Ed. P.K.Goel,M.Shahi, A.Sreenivas Kumar, R.K.Singh.. Cath Cardiovasc. Diagn. Nov.97.
6. Results of Inoueballoon mitral valvotomy in juvenile rheumaticmitral stenosis. Let. to Ed. A.Kapoor, A. Sreenivas Kumar. Int. J. Cardiol. 1998,66: 97-98
7. Astudy of clinical profile of cases of “Aplastic Anemia and their response to treatmentwith Cyclosporine-A’’. A.Sreenivas Kumar, Vijay Mohan, RaghuramuluM, Chandrakant P, Satyanarayana Ch, Venkateshwar Rao.R. Post Graduate Medical Clinicsof Osmania 1994,1.1.
8. NewerAntimicrobials. Review article. A.SreenivasKumar, Vijay Mohan, Leelavati,Satyanarayana Ch, Sahay B.K, Prakasham A. PostGraduate Medical Clinics of Osmania 1994,1.1.
9. Postmyocardial infarct patient. Review article. A.Sreenivas Kumar, Promod Kumar,A.K.Srivastava, P.Krishnam Raju. PostGraduate Medical Clinics of Osmania 1994,1.2.
10. Respiratory Failureand arterial blood gas analysis. Emergency Medicine review. A. SreenivasKumar, P.VijayMohan, Raghuramulu M, Chandrakant P, Satyanarayana Ch. Post Graduate Medical Clinicsof Osmania 1994,1.2.‍
11. Percutaneous closure of theductus by controlled release coils. A.Sreenivas Kumar,    Aditya Kapoor, N.Sinha, M.Shahi, P.K.Goel, S.Radhakrishnan, S.Shrivastava. Asian Annals of Cardiovascular and thoracic sugery.‍
12. Angiographic sizingof the patent ductus arteriosus- Relevance in the coil era. A.Sreenivas Kumar, P.K.Goel,M.Shahi. Int Journal of Cardiol‍
13.  Inoueballoon mitral commissurotomy(IBMC) in patients with atrial septal aneurysm(ASA). A.Sreenivas Kumar, P.K.Goel,A.Kapoor, C.V.Umeshan, N.SinhaInt. Journal of Cardiol..
14. Effect of Inoue Balloonmitral valvotomy in patientswith severe PAH-Immediate andlong term results. C.V.Umeshan, A.SreenivasKumar, A.Kapoor, N.Sinha, P.K.Goel.           Journal Of Heart Valve & Disease,1999.
15. Inoue balloonmitral commissurotomy(IBMC) in patientswith atrial septal aneurysm(ASA).PKGoel,A.Sreenivas Kumar,AKapoor,NGarg,Int.Journal Of Cardiology2001.‍
16. Non-invasive evaluation of Coronoryflow collaterals- An echo and angio correlation-Anne Anjaneyulu, K.Raghu, A.SreenivasKumar, P.Krishnam Raju, P.RaghavaRaju American Society of Echocardiography June 2008
17. Nephrotoxicity of Iodixanol versus iopamidol in patients with chronickidney disease and diabetes mellitusundergoing coronary angiographic procedures –Warren Lasky, Peter Aspelin, Charles Davidson,Sreenivas Kumar etal. Am.HeartJournal 2009;158.
18. Retrograde Transcatheter Closure of Ventricular Septal Defectsin Children Using The Amplatzer Duct Occluder II Nageswara Rao Koneti,* MD, DM, RaghavaRaju Penumatsa, MD, DM,Vasudevan Kanchi, MBBS, DCH, Sreenivas Kumar Arramraj,MD, DM, Cath CardioVasc. Interventions 2011.‍
19. Renal Denervation –DrVenkatSram & Dr.Sreenivas KumarArramraju , Journal of Hypertension 2014( Naturegp. Publication).
20. Indigenous Stent Technologies- Examining Clinical Data – ReviewArticle in Int.Cardiology 2015 (Future Medicine Publication).
21. PharmacoInvasive approach – A new paradigm in Acute MIManagement – STEMI India text Book -2015.
22. Renal Sympathetic Denervation – Current Status & FutureProspects – CSI Hypertension reviews2020.
23. Dual Antiplatelet therapyUsage Beyond One year/ One month : trials versusreal world Practice– CSI year book 2020.‍
24. ‍Takasubo Cardiomyopathy– CSI year Book 2019.‍
25. CSI- NIC Data 2018 – IHJ 18.07.2020.‍
26. The report of Indian CoronaryIntervention Data of 2017-IHJ 04. 2019.
27. Is Cardiology in India ready to shift from Solo to GroupPractice – European HJ Feb 2019.
28. Invasive Hemodynamic Assessment of Coronary Stenosis – Utility& Pitfalls – CSI year Book 2018.
29. Cardiovascular Disease in India – A 360 Degree Overview –National Medical Journal of Armed forcesIndia 2019.
30. Reversible LV Dysfunction after Transcatheter Aortic Valvereplacement (TAVR) – IJCC2020.

Papers Published

1. Study of Multi-Drug Resistant Salmonella infections. At A.P.I. Conference, Kakinada,1991.
2. A case report of Pseudomonas pyogenic meningitis - its complications and management. At A.P.I. Conference, Kakinada ,1991.
3. A study of clinical profile of cases of “ Aplastic Anemia and their response to treatment with Cyclosporine-A’’. At A.P.I. Conference, Kurnool, 1994. (Award Session)
4. A study of clinical profile of cases of sickle cell disorder in adults. At A.P.I. Conference, Kurnool, 1994.
5. A study of five cases of full blown AIDS. At A.P.I. Conference, Kurnool, 1994. (Award Session).
6. Scoring system to differentiate cirrhotic from non-cirrhotic portal hypertension.
7. At A.P.I. Conference, Kurnool, 1994. Inoue balloon mitral valvotomy in patients with severe sub valvular pathology. At C.S.I. Conference, Bangalore,1996. Indian HeartJournal (abstract) Sept- Oct.1996.
8. Inoue balloon mitral valvotomy in juvenile rheumatic mitral stenosis. At C.S.I. Conference, Bangalore,1996. Indian Heart Journal(abstract)Sept-Oct.1996.
9. Angiographic sizing of the patent ductus arteriosus (PDA)- relevance in the coil era. At C.S.I. Conference, Bangalore,1996. Indian Heart Journal(abstract)Sept- Oct.1996.
10. Inoue balloon mitral valvotomy in mitral stenosis with severe pulmonary arterial hypertension. At C.S.I. Conference, Bangalore,1996. Indian Heart Journal (abstract) Sept-Oct.1996.
11. Inoue balloon mitral vavotomy in patients older than 40 years. At C.S.I. Conference, Bangalore,1996. Indian Heart Journal(abstract)Sept-Oct.1996.
12. Small(<21mm) aortic prostheses-A clinical and hemodynamic evaluation. At C.S.I. Conference, Calcutta,1997. Indian HeartJournal(abstract)Nov-Dec.1997.
13. Pretransplant coronary arteriography in diabetic patients with end stage renal disease. At C.S.I. Conference, Calcutta,1997. Indian Heart Journal(abstract)Nov- Dec.1997.
14. Inoue balloon mitral commissurotomy(IBMC)- Predictors,Mechanisms and outcome of significant mitral regurgitation(MR). At C.S.I. Conference, Calcutta,1997. Indian Heart Journal(abstract)Nov-Dec.1997.
15. Inoue balloon mitral commissurotomy(IBMC) in patients with atrial septal aneurysm(ASA).   At   C.S.I.   Conference,   Calcutta,1997. Indian Heart Journal(abstract)Nov-Dec.1997.
16. Decreasing subacute thrombosis-is it high pressure post dilatation or something else? At C.S.I. Conference, Calcutta,1997. Indian Heart Journal(abstract)Nov- Dec.1997
17. Balloon Mitral valvotomy in juvenile mitral stenosis : An Indian experience . S.Shrivastava, S.Radhakrishnan, A.Kapoor, N.Sinha, A.Sreenivas Kumar, P.K.Goel. Presented at the 2nd World Congress of Paediatric Cardiology and Cardiac Surgery, Honolulu, Hawai, May 1997.
18. Successful management of recurrent acute ischemic coronary events in Primary Antiphospholipid Syndrome. At International Symposium/C.M.E. on prevention of CAD. 11th Annual Conference of the Indian Society for Atherosclerosis Research, New Delhi,November 1998.
19. Atherosclerotic CAD and angina in patients with congenital coronary anomolies. At International Symposium/C.M.E. on prevention of CAD. 11th Annual Conference of the Indian Society for Atherosclerosis Research, New Delhi,November 1998.
20. Atherosclerotic CAD in patients with End Stage Renal Disease. At International Symposium/C.M.E. on prevention of CAD. 11th Annual Conference of the Indian Society for Atherosclerosis Research, New Delhi,November 1998.
21. Inoue Balloon mitral valvotomy in patients < 12 years. At C.S.I. Conference, Bombay,1998. Indian Heart Journal (abstract) Nov-Dec 1998.
22. Analysis of etiology of moderate to severe MR in patients with < 12 years of age. At C.S.I. Conference, Bombay,1998. Indian Heart Journal (abstract) Nov-Dec 1998.
23. Effect of oral Nicorandil on chronic MR and/or AR - A Clinical and Echocardiographic study. At C.S.I. Conference, Bombay,1998. Indian Heart Journal (abstract) Nov-Dec 1998.
24. Predictors , Mechanisms and Outcome of occurrence of MR post Inoue balloon mitral valvotomy at WorldHeart Symposium, 1999, London.
25. Coil Occusion of Coronary Cameral fistula-World Pediatric Cardiology Conference.

‍